Community participation and perspectives of Ambondrolava mangrove restoration project

Madagascar’s mangrove forests are intertidal ecosystems that provide numerous valuable ecosystem services but are nonetheless under pressure from large amounts of deforestation. On the southwestern coast of Madagascar, the village of Ambondrolava practices community led management of the mangrove and its resources. This research project studied the evolution of the mangrove area using GIS data, and investigated, through interviews, the relationship between the local community of Ambondrolava and the organizations that manage the mangrove ecosystem. From 2000 to 2018, the zone of the mangrove has experienced a net loss in area every year, despite reforestation efforts. Most community members interviewed expressed the importance of the mangrove forest and therefore its conservation, as well as benefits gained from the two management organizations, VOI Mamelo Honko and Reef Doctor Honko Project. However, participants also expressed discontent with the dishonesty and unreliability of the VOI leaders. To ensure the success of the conserving the mangrove, these issues of trust and transparency must be addressed, and alternative sources of income and food should be instituted to reduce anthropological pressure on the mangrove and improve community livelihood

Facilitators and barriers to the implementation of a Mobile Health Wallet for pregnancy-related health care: A qualitative study of stakeholders’ perceptions in Madagascar

Financial barriers are a major obstacle to accessing maternal health care services in low-resource settings. In Madagascar, less than half of live births are attended by skilled health staff. Although mobile money-based savings and payment systems are often used to pay for a variety of services, including health care, data on the implications of a dedicated mobile money wallet restricted to health-related spending during pregnancy–a mobile health wallet (MHW)–are not well understood. In cooperation with the Madagascan Ministry of Health, this study aims to elicit the perceptions, experiences, and recommendations of key stakeholders in relation to a MHW amid a pilot study in 31 state-funded health care facilities. We conducted a two-stage qualitative study using semi-structured in-depth interviews with stakeholders (N = 21) representing the following groups: community representatives, health care providers, health officials and representatives from phone provider companies. Interviews were conducted in Atsimondrano and Renivohitra districts, between November and December of 2017. Data was coded thematically using inductive and deductive approaches, and found to align with a social ecological model. Key facilitators for successful implementation of the MHW, include (i) close collaboration with existing communal structures and (ii) creation of an incentive scheme to reward pregnant women to save. Key barriers to the application of the MHW in the study zone include (i) disruption of informal benefits for health care providers related to the current cash-based payment system, (ii) low mobile phone ownership, (iii) illiteracy among the target population, and (iv) failure of the MHW to overcome essential access barriers towards institutional health care services such as fear of unpredictable expenses. The MHW was perceived as a potential solution to reduce disparities in access to maternal health care. To ensure success of the MHW, direct demand-side and provider-side financial incentives merit consideration

Positive Outcomes in Cardiac Rehabilitation: The Little Program That Could

Permission to include article in the University of Lethbridge Institutional Repository granted by the Canadian Council of Cardiovascular Nurses (CCCN).Cardiac rehabilitation programs (CRPs) are receiving increasing attention because they restore, maintain, or improve both physiologic and psychosocial client outcomes (Evenson, Rosamond & Luepker, 1998). However, less attention has been paid to the effect such programs may have on the health-related quality of life of participants. The objective of this study was to measure health-related quality of life outcomes before and after participation in a CRP. Participants were 64 clients entering one of five CRP groups at the Lethbridge Regional Hospital in southern Alberta. Participants completed the Short Form 36 Health Survey (SF-36) (Ware, 1997) both at the beginning and at the end of one 13-week CRP intervention. The SF-36 examines eight health concepts: physical functioning (PF), role-physical (RP), bodily pain (BP), general health (GH), vitality (VT), social functioning (SF), role-emotional (RE), and mental health (MH). Analysis showed a significant difference between the pre-test and post-test scores for six of the eight categories. Larger effect sizes were found for PF (d=.746), RP (d=657), and VT (d=.593). Smaller effects were found for BP (d=.299j, SF (d=.337J, and RE (d=.271). The findings of this study highlight improved health-related quality of life outcomes for clients participating in comprehensive cardiac rehabilitation programs

Folk Medicine in the Philippines: A Phenomenological Study of Health-Seeking Individuals

Background: Folk medicine refers to traditional healing practices anchored on cultural beliefs of body physiology and health preservation. Reflective of indigenous heritage, it fosters a better understanding of health and disease, healthcare systems, and biocultural adaptation. In the Philippines, Quiapo is a well-known site for folk medicine services, cultural diversity, religious practices, and economic activities. Methods: This study utilized a phenomenological approach to comprehend the lived experiences of health-seeking individuals and the meaning behind their acquisition of folk medicine products. Using convenience sampling, seven participants acquiring folk medicine products in Quiapo on the day of data collection were approached and interviewed on separate instances. The collected data subsequently underwent thematic analysis. Results: Analysis revealed three emergent themes: health-seeking behavior, sources of knowledge, and folk medicine utilization. Health-seeking behavior was linked with the participants’ purpose of going to Quiapo, reasons for utilizing folk medicine, experiences in using folk medicine, and beliefs associated with the product bought. Sources of knowledge tackled the participants’ sources of information about Quiapo and its products. Folk medicine utilization relates to the type of product bought, its perceived medicinal use, and its history of usage. Conclusion: Folk medicine is perceived to be effective alleviating health concerns. The acquisition of such products is attributed to satisfaction from prior experience, distrust in the current healthcare system, family tradition, and intention to supplement existing medical treatment. This study provides health professionals a better understanding of patients who patronize folk medicine, subsequently aiding them in providing a holistic approach to treatment

Jellyfication of marine ecosystems as a likely consequence of overfishing small pelagic fishes: Lessons from the Benguela

Changes in two contrasting ecosystems of the Benguela upwelling region, one dominated at mid-trophic level by jellyfishes (Namibia, northern Benguela ecosystem, where small pelagic fish abundance has been severely depleted) and one still dominated by small pelagic fishes (South Africa, southern Benguela) were compared in an effort to determine ecosystem trajectories under different exploitation regimes. The role of small pelagic fishes (clupeoids) was highlighted in the context of their importance in maintaining interactions in marine ecosystems. In particular, we examined trophic cascades and possible irreversible changes that promote the proliferation of jellyfishes in marine systems. We found that the presence of large populations of small pelagic fishes has a fundamental role in preserving beneficial trophic interactions in these marine ecosystems. The implications of trophic cascades, such as those observed in the northern Benguela, for ecosystem-based management were apparent. In addition, this comparison provides contrasting case studies to inform the development of management scenarios that avoid ecosystem shifts that affect predators and reduce the value of fisheries production.Web of Scienc

How Carvedilol activates β₂-adrenoceptors

Carvedilol is among the most effective β-blockers for improving survival after myocardial infarction. Yet the mechanisms by which carvedilol achieves this superior clinical profile are still unclear. Beyond blockade of β(1)-adrenoceptors, arrestin-biased signalling via β(2)-adrenoceptors is a molecular mechanism proposed to explain the survival benefits. Here, we offer an alternative mechanism to rationalize carvedilol’s cellular signalling. Using primary and immortalized cells genome-edited by CRISPR/Cas9 to lack either G proteins or arrestins; and combining biological, biochemical, and signalling assays with molecular dynamics simulations, we demonstrate that G proteins drive all detectable carvedilol signalling through β(2)ARs. Because a clear understanding of how drugs act is imperative to data interpretation in basic and clinical research, to the stratification of clinical trials or to the monitoring of drug effects on the target pathway, the mechanistic insight gained here provides a foundation for the rational development of signalling prototypes that target the β-adrenoceptor system

Support for UNRWA's survival

The United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) provides life-saving humanitarian aid for 5·4 million Palestine refugees now entering their eighth decade of statelessness and conflict. About a third of Palestine refugees still live in 58 recognised camps. UNRWA operates 702 schools and 144 health centres, some of which are affected by the ongoing humanitarian disasters in Syria and the Gaza Strip. It has dramatically reduced the prevalence of infectious diseases, mortality, and illiteracy. Its social services include rebuilding infrastructure and homes that have been destroyed by conflict and providing cash assistance and micro-finance loans for Palestinians whose rights are curtailed and who are denied the right of return to their homeland

Speaker Sex Perception from Spontaneous and Volitional Nonverbal Vocalizations.

In two experiments, we explore how speaker sex recognition is affected by vocal flexibility, introduced by volitional and spontaneous vocalizations. In Experiment 1, participants judged speaker sex from two spontaneous vocalizations, laughter and crying, and volitionally produced vowels. Striking effects of speaker sex emerged: For male vocalizations, listeners' performance was significantly impaired for spontaneous vocalizations (laughter and crying) compared to a volitional baseline (repeated vowels), a pattern that was also reflected in longer reaction times for spontaneous vocalizations. Further, performance was less accurate for laughter than crying. For female vocalizations, a different pattern emerged. In Experiment 2, we largely replicated the findings of Experiment 1 using spontaneous laughter, volitional laughter and (volitional) vowels: here, performance for male vocalizations was impaired for spontaneous laughter compared to both volitional laughter and vowels, providing further evidence that differences in volitional control over vocal production may modulate our ability to accurately perceive speaker sex from vocal signals. For both experiments, acoustic analyses showed relationships between stimulus fundamental frequency (F0) and the participants' responses. The higher the F0 of a vocal signal, the more likely listeners were to perceive a vocalization as being produced by a female speaker, an effect that was more pronounced for vocalizations produced by males. We discuss the results in terms of the availability of salient acoustic cues across different vocalizations